Structure of PDB 8i9y Chain CH Binding Site BS01 |
| >8i9y Chain CH (length=542) Species: 759272 (Thermochaetoides thermophila DSM 1495)
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TGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKF
TQETCSEKFGAIISSFPVLSDQHPFHRDLMNILYDADHFKVALGQISTAK
NLIETISRDYVRLLKYAQSLYQCKQLKRAALGRMATLIKRLKDPLIYLDQ
VRQHLARLPDINPTTRTLLVAGFPNVGKSSFVRSVTRADTPVEPYAFTTK
SLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVTALAHLRAAVLY
FMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPEM
QQEINDLTKSGEVEILRASCATQEGVQEVKNHVCERLLVERVSQKLKAGT
HSNGNIGTRLQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRR
VLARDIEEANGGAGVFNVDLRKDWILENPEWKYDKIPEIFDGKNVYDYID
PDIDAKLQALEEEEERLEKEGFYDEDEEEEEILQKAEYIREQHALIRNEA
KMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVDTEAIGLRA |
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| >8i9y Chain C1 (length=2609)
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|
uugaccucggaucagguaggaggacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaagc
ggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugga
gaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcca
cagagggugagagccccguauaguuggaagccaagccuguguaaagcucc
uucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaauu
ucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagug
aucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaau
uguugaaagggaagcgcuugugaccagacuugcgcccggcggaucauccg
guguucucaccggugcacuccgccgggcucaggccagcaucgguucuggc
ggggggauaaaggcccagggaauguggcuccuccgggaguguuauagccc
uggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugcu
ggcguaauggucaccagcgacccgucuugaaacacggaccaaggagucaa
gguuuugcgcgaguguuuggguguaaaacccgcacgcguaaggugagagc
uucggcgcaucaucgaccgauccugauguauucggauggauuugaguagg
agcguuaagccuuggacccgaaagauggugaacuaugcuuggauagggug
aagccagaggaaacucugguggaggcucgcugacgugcaagaucgucaaa
ucugagcaugggggcgaaagacuaaccaucuaguagcugguuaccgccga
aguuucccucaggauagcagugucgaccuucaguuuuaugagguaaagcg
aaugaacuuuaaauauguaagaagcccuuguuacuuaacugaacgugggc
auucgaauguaucgacacuagugggccauuuuugguaagcagaacuggcg
augcgggaugaaccgaacgcgggguuaaggugccggaguggacgcucauc
agacaccacaaaaggcguuaguacaucuugacagcaggacgguggccaug
gaagucggaauccgcuaaggacuguguaacaacucaccugccgaauguac
uagcccugaaaauggauggcgcucaagcgucccacccauaccccgcccuc
aggguagaaacgaugcccugaggaguaggcggccguggaggucagugacg
aagccuagggcgugagcccgggucgaacggccucuagugcagaucuuggu
gguaguagcaaauacuucaaugagaacuugaaggaccgaaguggggaaag
guuccaugugaacagcgguuggacauggguuagucgauccuaagccauag
ggaaguuccguuucaaaggggcacucgugccccguguggcgaaagggaag
ccgguuaauauuccggcaccuggauguggguuuugcgcggcaacgcaacu
gaacgcggagacgacggcgggggccccgggcagaguucucuuuucuucuu
aacggucuaucacccuggaaacaguuugucuggagauaggguuuaauggc
cggaagagcccgacacuucugucggguccggugcgcucucgacgucccuu
gaaaauccgcgggagggaauaauucucacgccaggucguacucauaaccg
cagcagguccccaaggugaacagccucugguugauagaacaauguagaua
agggcugucccuaucuacuaucuagcgaaaccacagccaagggaacgggc
uuggcaaaaucagcggggaaagaagacccuguugagcuugacucuaguuu
gacauugugaaaagacauaggagguguagaauaggugggagcuucggcgc
cagugaaauaccacuacuccuauuguuuuuuuacuuauucaaugugaaga
cauugucagguggggaguuccuuuagucccucgaaauuugaggcuagagg
agaaaaguuaccacagggauaacuggcuuguggcggccaagcguagcgac
gucgcuuuuuggaugcggcucuuccuaucauaccgaagcagaauucggua
agcguuggauuguucacccacuaauagggaacgugagcuggaccgucgug
agacagguuagucccuacugaugaacucgucgcaaugguaauucagcuua
guacgagaggaaccgcugauucagauaauugguuuuugcgguuguccgac
cgggcagugccgcgaagcuaccaucugcuggauaauggcugaacgccucu
aagucagaauccaugccagaacgcgacgauacuacccgcacguuguagac
guauaagaauaggcuccggccucguauccuagcaggcgauuccuccgccg
gccucgaaguggccgucgguaauucgcguauugcaauuuagacacgcgcg
ggaucaaauccuuugcagacgacuuagaugugcgaaaggguccuguaagc
aguagaguagccuuguuguuacgaucugcugaggguaagcccuccuucgc
cuagauuuc |
........................<<<<<<.....<<....>>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<..<<.......<<.<<<....>>>.>>.......>>....
<<<<<.<<<<<<<<<..<<<<<<..<<....<<<<......>>>>.((..
....<<<.....))>>>....>>..>>>.>>>..>>>>....>>>>>>>>
.>>........<<<<<<<........>>>>>>>.....<<<<<<......
>>>>>>..>>>..................................<<...
.>>...............<<<<....>>>>....................
..............<<<<.<<<<<<.<...<<.<<<<<<<<<.....<<<
<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<<
<<<<<.......<<<<<<<<......<<<<<....>>>>>.......>>>
>>>>>......>>>>>>>>>>>>>>>........<<...>>.....>>>>
>>>....>>>>>>>.>>>>..<<<<........>>>><<<<<<....<<<
<<<<<.<<<<..<<<..<<<<<.....>>>>>..>>>....<<<<<..<<
....>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>...
.>>>>.>>>>>>>>..<<.<...<<<<<<...<.<<<<<<<<<..<<<<.
..<<<<<<<....>>>>>>>...>.>>>..<<<<<........>>>>>..
>>>>>>>>>>.<<.<....>.>>.>>>>>>......>.>>...<<<<<..
..<.<<<....>>>.><<<<<<<<<<....<<.<<<<<<<.....<<<..
......>>.>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>
.....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>.
...<<<......>>>...<<<<<<<...<<<((......<<<<<<.....
<<..........<<<.<<<<<<<<<<.......<<<<<.<<<...<<...
......>>...>>>.........<<......>>...>>>>>...>>>>>>
>>>>>>>...........)).>>...>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>.<.<<<<<<<<.<<....
..<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>>
<<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<
...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<
<<....>>>........<<<<<......>>>>>....>>>....>>...<
<<<<........>>>>>))<<<<.<<<<.<<<....<<<....>>>....
...<<<<<<...<<<<.<<<<<<<<<<<<<.<<<<...((..>>>>.><.
..<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>
>>....><<<<<<<<....>>>>>>>>>>>>.>.>>>>>>>.>>>>....
.....>>>>>>.........>>>...>>>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<.
<<<......>>>>>>>>>..>>>>>>....>>....<<<<<........>
>>>>....<<<<<..<<<........<<<<<<.<<<<<<.<<<<<.<<<<
<<<<..<<<<<<<<<<<<<<<<<..........<<<<<..<<....>>..
..........>>>>>.>>>>>>>.>>>>>>>>>>...<<<<...>>>>..
...>>>>>>>>..>>>>>.<<<<<<<..<<<<<<...>>>>>>>>>>>>>
....>>>>>.>.>>>>>>.............<<<<<<...<<...>>...
>>>>>>.....((...<<<<<<<<<<..<.<<<<<<<......>>>>>>>
...>.<<<.....))..>>>.....>>>>>....>>>>>.<<<<<<<...
.>>>.>>>>....>>>.>>>>>....<<<<<<<..<<<<.<.<<<<<...
..............>>>>>.><<<<<...<<<<....<<<<<<<<<<)).
.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<..........
.>>>>>...>>>>.>>>>....>>>>>>>.....<<<<<.<<.<<<....
..<<.......<<<....>>>....>>........<<<<.....<<<.<<
<<<.......>>>>>.>>>....>>>>..............>>>>>.>>>
>>...<<<<<<<.............>>....<<<<<<<<<.<<<....<<
<<.<..<<<<<......>>>>>..>>>>>...>>>....>>>>..>>>>>
...>>>>>. |
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| PDB | 8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | K5 D18 I19 L21 S22 Q25 R26 R27 L28 P29 T30 Q31 I32 R33 P34 G35 R47 K48 E54 V69 L70 D88 K91 L94 Q96 T99 L103 K116 Y122 K125 K128 R129 A130 G133 R134 L138 R141 R158 P160 D161 R188 Y196 F198 V205 H207 N232 A414 G415 H499 R503 K510 S511 L512 K513 R515 R520 K521 |
Binding residue
(residue number reindexed from 1) | K4 D17 I18 L20 S21 Q24 R25 R26 L27 P28 T29 Q30 I31 R32 P33 G34 R46 K47 E53 V68 L69 D87 K90 L93 Q95 T98 L102 K115 Y121 K124 K127 R128 A129 G132 R133 L137 R140 R157 P159 D160 R187 Y195 F197 V204 H206 N231 A413 G414 H493 R497 K504 S505 L506 K507 R509 R514 K515 |
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| Enzyme Commision number |
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