Structure of PDB 7ajt Chain CH Binding Site BS01

Receptor Information
>7ajt Chain CH (length=465) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENPADKRRRLAKQYLENLKSEANDILTDIIASRLKEDVAEQQGRVFRYFG
DKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFA
YTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYD
EILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLA
FRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCV
TVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKEPLFFCEGSIDVV
SMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGET
DEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNL
RSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIAN
VSGARNGIYSAVIDQ
Ligand information
>7ajt Chain D4 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccgugagaaauagcuugguccgcaauccuuagcgguucggccaucu
auaauuuugaauaaaaauuuugccguugcuauggcgcgaugaucuaccca
uggguggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<.<.......<<...<<<.<<<.<<<<......>>>>>>>>>>..>
>.<<<<<......>>.>>>..<<<<......>>>>........>.<<<..
..>>>.>>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
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PDB7ajt Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		R151 G153 S264 E266 S267 R551 G558 R560
Binding residue
(residue number reindexed from 1)		R64 G66 S177 E179 S180 R446 G453 R455
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ajt, PDBe:7ajt, PDBj:7ajt
PDBsum7ajt
PubMed33326748
UniProtQ06506|RRP9_YEAST Ribosomal RNA-processing protein 9 (Gene Name=RRP9)

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