Structure of PDB 4v7l Chain CG Binding Site BS01

Receptor Information
>4v7l Chain CG (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW
Ligand information
>4v7l Chain CA (length=1495) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcggccguggucagcggcggacgggugaguaa
cgcgugggugaccuacccggaagagggggacaacccggggaaacucgggc
uaaucccccauguggacccgccccuugggguguguccaaagggcuuugcc
cgcuuccggaugggcccgcgucccaucagcuaguuggugggguaauggcc
caccaaggcgacgacggguagccggucugagaggauggccggccacaggg
gcacugagacacgggccccacuccuacgggaggcagcaguuaggaaucuu
ccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcc
cuucgggguguaaacuccugaacccgggacgaaacccccgacgaggggac
ugacgguaccgggguaauagcgccggccaacuccgugccagcagccgcgg
uaauacggagggcgcgagcguuacccggauucacugggcguaaagggcgu
guaggcggccuggggcgucccaugugaaagaccacggcucaaccgugggg
gagcgugggauacgcucaggcuagacggugggagagggugguggaauucc
cggaguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaag
gcagccaccugguccacccgugacgcugaggcgcgaaagcguggggagca
aaccggauuagauacccggguaguccacgcccuaaacgaugcgcgcuagg
ucucugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugg
ggaguacggccgcaaggcugaaacucaaaggaauugacgggggcccgcac
aagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuacca
ggccuugacaugcuagggaacccgggugaaagccuggggugccccgcgag
gggagcccuagcacaggugcugcauggccgucgucagcucgugccgugag
guguuggguuaagucccgcaacgagcgcaacccccgccguuaguugccag
cgguucggccgggcacucuaacgggacugcccgcgaaagcgggaggaagg
aggggacgacgucuggucagcauggcccuuacggccugggcgacacacgu
gcuacaaugcccacuacaaagcgaugccacccggcaacggggagcuaauc
gcaaaaaggugggcccaguucggauuggggucugcaacccgaccccauga
agccggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguu
cccgggccuuguacacaccgcccgucacgccaugggagcgggcucuaccc
gaagucgccgggagccuacgggcaggcgccgaggguagggcccgugacug
gggcgaagucguaacaagguagcuguaccggaaggugcggcugga
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<..>>>>>>>.>>>>>......<<......
.<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>
>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>
>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<
<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>........
<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<
<....>>>>.....>>>>....<<<<<........<<<<.....>>>>..
........>>>>>......<<<<<(((...<<<<<.....<<.)))>>..
.....>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<
...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>..
..>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<.<..<<<<
<<<.<..<<<......>>>.....>.>>>>>>>...>.......<<....
>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<..<<
<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<
<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<
.<<<<<<..<<<<<<<<<<......<<........>>..........<<<
<<<<......<<<<<.<<..<<<<<<<....>>>>>>>....<<.....>
>....>>.>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>
>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...
<<<.....>>>>.....>>>>>>>.....<<<<<....>>>>>.......
.>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>
>>>.....<<<<<<<.....<<<..<...<<<<....>>>>...>....>
>>.....>>>>>>>......<..<.<<<<<<<........>>>>>>>>..
.>.....>>>>>>....<<<<<<<..........>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<
...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>
.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v7l The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A2 R3 R4 R6 A7 R10 K29 M31 D33 G34 K36 N37 L38 I42 R76 R78 G81 G82 R94 R95 R102 N109 R114 A116
Binding residue
(residue number reindexed from 1)		A1 R2 R3 R5 A6 R9 K28 M30 D32 G33 K35 N36 L37 I41 R75 R77 G80 G81 R93 R94 R101 N108 R113 A115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v7l, PDBe:4v7l, PDBj:4v7l
PDBsum4v7l
PubMed20154709
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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