Structure of PDB 7aju Chain CF Binding Site BS01

Receptor Information
>7aju Chain CF (length=121) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPKAFPLADAALTQQILDVVQQAANLRQLKKGANEATKTLNRGISEFIIM
AADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITT
NDASAIKTQIYAVKDKIETLL
Ligand information
>7aju Chain D4 (length=223) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucaaggaucaucuauaggaaucgucacucuuugacucuu
cccacugaauccaacuugguugaugagucccauaaccuuuguaccccaga
gugagaaauagcuugguccgcaauccuuagcgguucggccaucuauaauu
uugaauaaaaauuuugccguugcuauggcgcgaugaucacccaugggugg
guacaaauggcagucugacaagu
..................................................
.............<<<<<.................<<<<<<<<<<<....
<........<<..<<<.<<<.<<<<......>>>>>>>>>>.>>..<<<<
<<....>>>.>>>..<<<<<....>>>>>........><<<<..>>>>>>
>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
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PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		G36 A37 N38 E39 K42 R46 E59 R95 V97 I98
Binding residue
(residue number reindexed from 1)		G32 A33 N34 E35 K38 R42 E55 R91 V93 I94
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030621 U4 snRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0000452 snoRNA guided rRNA 2'-O-methylation
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000494 box C/D sno(s)RNA 3'-end processing
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0005730 nucleolus
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtP39990|SNU13_YEAST 13 kDa ribonucleoprotein-associated protein (Gene Name=SNU13)

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