Structure of PDB 6rxx Chain CD Binding Site BS01

Receptor Information
>6rxx Chain CD (length=420) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFILTETSAGYALFKAIKYKEFAKFDSAAIAVEEASGILEGKVTPKLASL
LNELKDEKKVTLAVHDTKLSNSITKLPGINIKPISGSMTDDLFRAIRQHL
YNLIPGMEPSNFDEMNLGLAHSLSRHKLKFSPEKVDVMIVHAVALLDELD
KELNVMAMRVKEWYGWHFPELGKILPDNLSYARVVLALGLRTNAPNADLS
EILPPEIEAAVKAAADISMGTEISTEDYENIKLLAVQVVERSEYRRQLAE
YLQNRMKAISPNMTELIGALVGARLIAHSGSLVNLAKNPGSTIQILGAEK
ALFRALKTKHATPKYGIIYHASLVGQASGPNKGKIARQLAAKIALSVRTD
AFEDFPENADDETRAAVGIQARAKLENNLRLLEGKPLNKGVALGPNGIPV
GMPAKWDVKEARKYNIEADG
Ligand information
>6rxx Chain C2 (length=229) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgacaauacuucagagaaucauuucuauaguaguuguccucucuugug
uuuccuaaaggagccacagaucccacccggguugaugaacgagauccucg
gcgccagugagguccuuuacucucgcucuaccugcaaagguggcggucgc
gugccucgucucgcggcuguauagagaguggcgaugaucuguaccccgcg
gggugggugucgauggaagucugaccggc
..................................................
..........................<<<<......<.......<<<<<<
<<<<.<<...........<<<<<<...<<<<<<....>>>>>><<<<<<<
<.<......>.>>>>>>>>....>>>>>>.........>>.<<<<<<..>
>>>>>.>>>>>>>.>>>...>...>>>>.
Receptor-Ligand Complex Structure
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PDB6rxx Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution7.1 Å
Binding residue
(original residue number in PDB)
D173 H304 S317 T318 G323 A324 E325 K326 A327 A331 A337 T338 P339 K340 Y341 G359
Binding residue
(residue number reindexed from 1)
D147 H278 S291 T292 G297 A298 E299 K300 A301 A305 A311 T312 P313 K314 Y315 G333
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:6rxx, PDBe:6rxx, PDBj:6rxx
PDBsum6rxx
PubMed31378463
UniProtG0RYF6

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