Structure of PDB 7pbc Chain CCC Binding Site BS01

Receptor Information
>7pbc Chain CCC (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGC
DVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAH
VAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATL
RCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pbc Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
Resolution2.04 Å
Binding residue
(original residue number in PDB)
Y8 E64 K67 V68 H71 T74 V77 D78 Y85 Y100 Y117 T144 K147 W148 V153 L157 Y160 W168 Y172
Binding residue
(residue number reindexed from 1)
Y6 E62 K65 V66 H69 T72 V75 D76 Y83 Y98 Y115 T142 K145 W146 V151 L155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links