Structure of PDB 8oeq Chain CC Binding Site BS01

Receptor Information
>8oeq Chain CC (length=118) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGVKTFELRTKSKEQLESQLVELKQELATLKVQKLQRPSLPRIHTVRKNI
ARVLTVINLNQRENVRAFYAGKKYIPKDLRAKKTRALRRKLTKFEASQET
EKARKQRIAFPQRKFAIK
Ligand information
>8oeq Chain AS (length=3199) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauugcggu
uuaccgggccagcaucgguuuggagcggcaggauaauggcggaggaaugu
ggcacggcuucugcuguguguuauagccucugacgauacugccagccuag
accgaggacugcgguuuuuaccuaggauguuggcauaaugaucuuaaguc
gcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuug
gguguaaaacccguacgcguaaugaaagugaacgaaggugggggcccauu
agggugcaccaucgaccgauccugauguguucggauggauuugaguaaga
gcauagcuguugggacccgaaagauggugaacuaugccugaauaggguga
agccagaggaaacucugguggaggcucguagcgguucugacgugcaaauc
gaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuagua
gcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguu
uuaugagguaaagcgaaugauuagaagucuugggguugaaaugaccuuaa
cuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauugaac
guggacaauugaaugaagagcuuuuagugggccauuuuugguaagcagaa
cuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaugcacg
cucaucagacaccacaaaagguguuaguucaucuagacagccggacggug
gccgcuaaggaguguguaaacucaccggccgaaugaacuagcccugaaaa
uggauggcgcucaagcgugcuacuuauacuucaccgugauugcuguuuug
acgcuuucacgaguaggcaggcguggaggucagugacgaagccuuugcug
uaaagcugggucgaacggccucuagugcagaucuuggugguaguagcaaa
uauucaaaugagaacuuugaagacugaaguggggaaagguuccaugucaa
cagcaguuggacauggguuagucgauccuaagagauggggaagcuccguu
ucaacgugcuugauuuuucaggccaaccaucgaaagggaauccgguuaaa
auuccggaacuuggauauggauucuucacggcaacguaacugaaugugga
gacgucggcgugagcccugggaggaguuaucuuuucuucuuaacagcuua
ucacccuggaauugguuuauccggagauggggucuuauggcuggaagagc
gcgguaauuuugccgcguccggugcgcuuacgacgguccuugaaaaucca
caggaaggaauaguuuucaugccaagucguacucauaaccgcagcagguc
uccaagguuaacagccucuaguugauagaauaauguagauaagggaaguc
ggcaaaauagauccguaacuucgggauaaggauuggcucuaaggaucggg
cacguuuaacgaucaacuuagaacugguacggacaaggggaaucugacug
ucuaauuaaaacauagcauugugauggucagaaagugauguugacacaau
gugauuucugcccagugcucugaaugucaaagugaagaaauucaaccaag
cgcggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugc
cucgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacu
gucccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggca
gaaucagcggggaaagaagacccuguugagcuugacucuaguuugacauu
gugaaaagacauggaggguguagaauaagugggagcuucggcgccgguga
aauaccacuaccucuauaguuuuuuuacuuauucaaugaagcggagcugg
aggucaaacuccacguucuagcauuaagcccucugggcgauccggguuga
agacauugucagguggggaguuuggcuggggcggcacaucuguuaaacga
uaacgcagguguccuaagggggacucauggagaacagaaaucuccaguag
aacaaaaggguaaaaguccccuugauuuugauuuucagugugaauacaaa
ccaugaaaguguggccuaucgauccuuuagucccucggaauuugaggcua
gaggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagc
guucauagcgacauugcuuuuugauucuucgaugucggcucuuccuauca
uaccgaagcagaauucgguaagcguuggauuguucacccacuaauaggga
acgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacug
augaauguuaucgcaauaguaauugaacuuaguacgagaggaaccguuca
uucagauaauugguuuuugcggcugucugaucaggcaacgccgcgaagcu
accaucugcuggauuauggcugaacgccucuaagucagaauccaugcuag
aacgcgaugauuuuugcccugcacauuuuagauggauacgaauaagacuu
uuuagucgcuggaccauagcaggcuggcaacggugcgcuuagcggaaagg
cuuugugcgcuugccggcggauagcaaugucaacaugcgcggggauaaau
ccuuugcauacgacuuagauguacaacggaguauuguaagcaguagagua
gccuuguuguuacgaucugcugagauuaagcucuuguugucugauuugu
.......................<<<<<<.....<......>......>>
>>>.>.........<<....>>..<<<<<......<<.....>>.....>
>>>>..<<<...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<...<<<<<<<<<<<<.<<<<<<<.....<<<<......>>>
>.(.......<<<......)>>>....>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<.........
...>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<<<<<.....
.<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>>>.>>>>>>
>>>>........<<<....>>>.....>>>>>>>....>>>>>>>>>>>>
..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<..<<
<<<.....>>>>>..>>>...<<....>>.......<<<<<..<<<<...
.>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>....
>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<........>>
>>>>>>....>>>>>>>>>...<<.......>>......>>>>>>...>.
.>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<<.<<
<<<<<.....<<<....<<<....<<<<...<<<<<.......>>>>>.>
>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<......>>>>
>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>
.>>>>....<<<..[...>>>...<<<<<<<..<<<<(((.....<<<<<
<.....<<.....]....<<<.<<<<<<<<<<.......<<<<<.<<<..
.>>>.........<<....>>...>>>>>...>>>>>>>>>>>>>.....
.....))).>>...>>>>>>.>>>>..>>>>>>><<<<<..<<.......
..>>..>>>>>....>>>>>>..<<<<<<<<.<<......<<<<..<<<.
...>>>.>>>>...>>>>>>>>>>........>>>>>><<.....<<...
..<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>...
.......<<<<<<....>>>>>>......>>....>>...<<<<<.....
...>>>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<
...<<<<.<<<<<<<.<<<<<<<<<<..[[[..>>>>>><...<<<<<..
..<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<
<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>
>>..........>>>..>>>>>>>>>>>>..>>.....<<......>>>>
>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<......
...<.....<<<<<.....<..>......>>>>><<.<<<<<<<<<<<..
.........>>>>>..>>>>>>.>>............<<<<<<<<<..<<
<.........>>>..<<<<<<<....<<<<.....>>>>......>>>>>
>>...<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>
>>.>>>>..>>>>><<<<<<.......>>>>>>........<........
...<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>
..>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>..
..<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<..
<<<<<<<<<<<<...<<.................<......>........
............>>.>>.>>>>>>>>>>...<<<<<.....<<<<..<<<
<<......>>>>>..............<<<<...>>>>..>>>>..>>>>
>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<.......
....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>....
.<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>
.<<<....>>>.>>)))......<<<<<<<..<<<<.))))))>>>>>>>
>>>>.........>>>>..>>>>>>.......<<.<...<<<<<<...<<
.......>>...>>>>>>....>.>.>.......<<<<<.<<<<<<..<.
<<<<<<<......>>>>>>>...>.<<<.........>>>.....>>>>>
..>...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>
>>....<<<<<<<<..<<<<.<.<<<<<.................>>>>>
.><<<<<...<<<<....<<<<<<<<<<]]].>>>>>..>>>>>...>>>
>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>.
...>>>>>>>>.....<<<<<<.<<<.<.....<<..........<<<<.
...>>>>......>>.......<<<<<<...<<<<<<<..<<<......>
>>..>>>>>>>.>>>>>>..............>.>>>.>>>>>>..<<<<
<<<.............>>....<<<<<<<<<.<<<....<<<<....<<<
<<......>>>>>...>>>>...>>>....>>>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
G72 Y75 R81 R86 R90 T93 K94 F95 A97 S98 K103 K106 R108 I109 K115
Binding residue
(residue number reindexed from 1)
G71 Y74 R80 R85 R89 T92 K93 F94 A96 S97 K102 K105 R107 I108 K114
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