Structure of PDB 8i9t Chain CB Binding Site BS01

Receptor Information
>8i9t Chain CB (length=260) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDPDQTLKACKALLAHIKKAAAAPRPDGKQNLLADEESTVAETPIWLTLT
TKKHIHDSHRLQPGKIILPHPLNTSEEISVCLITADPQRFYKNAVADEFP
EDLRAKIGRVIDISHLKAKFKAYEAQRKLFSEHDVFLADTRIINRLPKAL
GKTFYKTTTKRPIPVVLMAQRDPLENANARPIPEIVAEIRKAIGAALVHL
SPSTNTAIKVGYANWEPEKLAANIETVIRELVERFVPQKWQNVRNFYVKG
PETAALPIYQ
Ligand information
>8i9t Chain C3 (length=98) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaccaucaagcccugggcuuguguuggggacccgcggcugcucgcgggc
ccugaaaagcaguggcgggcucgcuggcgggugccagccguaaaaccc
.......<<<<<<...>>>>>>....<<<<.<<<<<<<....>>>>>>>>
>>>.........<<<<<<<<<<<<..>>>>>>.>>.>>>>........
Receptor-Ligand Complex Structure
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PDB8i9t Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
S75 H76 L78 A102 K138 Y140 E141 R144 R158 N161 R162 P164 G168 K169 Y172 K173 T174 T175 T176 R206 S236 S238 N240 R279 K284 E287
Binding residue
(residue number reindexed from 1)
S58 H59 L61 A85 K121 Y123 E124 R127 R141 N144 R145 P147 G151 K152 Y155 K156 T157 T158 T159 R171 S201 S203 N205 R244 K249 E252
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000470 maturation of LSU-rRNA
Cellular Component
GO:0022625 cytosolic large ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8i9t, PDBe:8i9t, PDBj:8i9t
PDBsum8i9t
PubMed37129998
UniProtG0S7X0

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