Structure of PDB 8b6g Chain CB Binding Site BS01

Receptor Information
>8b6g Chain CB (length=285) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AESNDATSICLESISGTIKGLQKANYVVEHNPNLTSEEKKHLKQFLVYRY
NPADPHDQPKYVSYWCDIKKFPPMFLDAILYIKNELDPTLSIRRSCREGI
CGSCAVNCDGLHTLACISGFNRDLSKPTIITPLGHMFILKDLVVDMTNFY
AQYKMIEPYLKRKTPKPDANKEYPQSPEQRALLDGLYECVLCAACSTSCP
SYWWHPDRYLGPAILQQAYRWIVDSRDEYTQERIERIAEDVRLDDCQQIG
MCSFTCPKGLNPQLSLKNLMDMVKDFRQKRIEQEV
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8b6g Chain CB Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6g Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C122 R123 G125 C127 G128 C130 C142
Binding residue
(residue number reindexed from 1)		C96 R97 G99 C101 G102 C104 C116
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0008177 succinate dehydrogenase (quinone) activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051538 3 iron, 4 sulfur cluster binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b6g, PDBe:8b6g, PDBj:8b6g
PDBsum8b6g
PubMed36949187
UniProtI7M403

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