Structure of PDB 8bqs Chain CA Binding Site BS01

Receptor Information
>8bqs Chain CA (length=599) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTDKYTVIDHTYDAIVVGAGGAGLRAAFGLVEEGFKTACITKLFPTRSHT
VAAQGGINAALGNMTEDDWKWHFYDTVKGSDWLGDQDAIQYMTREAPAAV
LELESYGLPFSRTPEGKIYQRAFGGQSLKFGKGGQARRTACAADRTGHAM
LHTLFGRSLAYNCNFFIEYFVIDLIMDEEGACRGVICMSMADGSIHRIRA
HYTVLAAGGYGRSYLSCTAAHTCTGDGMALATRAGLPLEDPEFVQFHPTG
IYGSGCLMTEGCRGEGGILVNSNGEAFMEKYAPTAKDLASRDVVSRAMTI
EILEGRGVGPKKDHIFLQLHHLSPETLHQRLPGISETARIFAGVDVTKEP
APVVPTVHYNMGGVPTNWKTEVITQDKNGKDKIVPGLLAAGENACASVHG
ANRLGANSLLDIVVFGRAAAKLVKEKLKPGTPHKDLPKNAGEQALARLDK
YRFANGEYTTHHVRTAMQETMQRHAAVFRIEKLMAEGVQKLDHIYEQSKS
LKTFDRGLVWNTDLIETLELENLLLCSKQTLLAGLLRKESRGAHARDDFK
ERDDKNWMKHSLTWIKDVNTGKTEVTYRDVINHTLDSEVTPVPPAKRSY
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8bqs Chain CA Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8bqs Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
Resolution2.9 Å
Binding residue
(original residue number in PDB)		Y396 N397 M398 E429
Binding residue
(residue number reindexed from 1)		Y359 N360 M361 E392
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0008177 succinate dehydrogenase (quinone) activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006121 mitochondrial electron transport, succinate to ubiquinone
GO:0022900 electron transport chain
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8bqs, PDBe:8bqs, PDBj:8bqs
PDBsum8bqs
PubMed
UniProtQ23DI3

[Back to BioLiP]