Structure of PDB 8b6g Chain CA Binding Site BS01

Receptor Information
>8b6g Chain CA (length=599) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTDKYTVIDHTYDAIVVGAGGAGLRAAFGLVEEGFKTACITKLFPTRSHT
VAAQGGINAALGNMTEDDWKWHFYDTVKGSDWLGDQDAIQYMTREAPAAV
LELESYGLPFSRTPEGKIYQRAFGGQSLKFGKGGQARRTACAADRTGHAM
LHTLFGRSLAYNCNFFIEYFVIDLIMDEEGACRGVICMSMADGSIHRIRA
HYTVLAAGGYGRSYLSCTAAHTCTGDGMALATRAGLPLEDPEFVQFHPTG
IYGSGCLMTEGCRGEGGILVNSNGEAFMEKYAPTAKDLASRDVVSRAMTI
EILEGRGVGPKKDHIFLQLHHLSPETLHQRLPGISETARIFAGVDVTKEP
APVVPTVHYNMGGVPTNWKTEVITQDKNGKDKIVPGLLAAGENACASVHG
ANRLGANSLLDIVVFGRAAAKLVKEKLKPGTPHKDLPKNAGEQALARLDK
YRFANGEYTTHHVRTAMQETMQRHAAVFRIEKLMAEGVQKLDHIYEQSKS
LKTFDRGLVWNTDLIETLELENLLLCSKQTLLAGLLRKESRGAHARDDFK
ERDDKNWMKHSLTWIKDVNTGKTEVTYRDVINHTLDSEVTPVPPAKRSY
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8b6g Chain CA Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6g Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Y396 N397 M398 G399 E429
Binding residue
(residue number reindexed from 1)		Y359 N360 M361 G362 E392
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0008177 succinate dehydrogenase (quinone) activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006121 mitochondrial electron transport, succinate to ubiquinone
GO:0022900 electron transport chain
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b6g, PDBe:8b6g, PDBj:8b6g
PDBsum8b6g
PubMed36949187
UniProtQ23DI3

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