Structure of PDB 7am2 Chain CA Binding Site BS01

Receptor Information
>7am2 Chain CA (length=537) Species: 5689 (Leishmania tarentolae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLEAVIRVQSTDAHVTEVDANGGGAFLEKAPKGRWRKISRSKTLLVEDTA
TPFSNSDKSFSPRVQSYGEYVRRIGKLPEGRPLLRFAMFRDGYSLDSVCH
RLRYEIGVPHDGVYLHEPPGGSFAAVTQFGVAVGVTREQLPHASRHYNVH
ALIFDDRGYHALDELPRLSVAPQAYLHRILLRCVSGDEAAVAQRLRHLSS
NGFINYFGLESFGIGSNTLFDMAAFAFRREPHRSVGAYLQTLAECSPLHH
QPYLSYANAEESTVAGAVAEWLRVCERAKLPRETRELLRKLHCYHLSQCH
PSDATTISMEDVWKACPIMHRAEQSAAAFVWNAMASQRLLSFGSRPVKGD
LVCRIGNRGAIEIAEVASDTDASHYTIDDVVLPIPCGGTPAAELRYPTHS
VNEAFFTQFAKKHSLSFLFNSGVDPTPRAAATLGPYRRLVSRPRNLQAAV
LQDPSSCAALKSDLFLLQEHQPTEGWSLDYRQRVREPSNFNVSERFRERM
SCIRKRRAGEHSVALAFVLPAGSSPWVALREAFHMHY
Ligand information
>7am2 Chain 1 (length=797) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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........<<....>.>..............<<....<<<<<<<.....<
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....>>>...<<<.....>>>.....>>>>>>>.......>>........
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...........<<.............<<<<<...>>>>>.....<<<<<<
...<<<<<<<...>>>>>>>.>>>>>>...............>>......
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Receptor-Ligand Complex Structure
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PDB7am2 Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K113 L115 P123 S125 Q136
Binding residue
(residue number reindexed from 1)		K42 L44 P52 S54 Q65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7am2, PDBe:7am2, PDBj:7am2
PDBsum7am2
PubMed33168716
UniProtQ4QGU5

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