Structure of PDB 7qep Chain C8 Binding Site BS01

Receptor Information

>7qep Chain C8 (length=141) Species: 284813 (Encephalitozoon cuniculi GB-M1)

NYTYDPAEVQYIVRIHNTNIDGTKRIPFALTKIRGIGIRIATAICKRLGI
DLRKRAGEMGEDEMKRISDAILDPASVGIPESYMNHQRDIIDGTTSHLIG
TRLDADLRMMIERGKKNKRIRAYRLDVGLKVRGQRTKSNGR

Ligand information

>7qep Chain 3 (length=1295)

aucagguugauucugccugacguggaugcuauucucuggggcuaagccau
gcaugcuugugaacucuuugugggggauuagcggacggcucagugauagc
acgaugauuuguuugcgggaugagcaguagcugcgggaaacugcagauag
uggucugccccuguggggguuggcaaguaaguugugggccuaucagcugg
uaguuaggguaauggccuaacuaggcgcagacgggauacgggggaucagg
guuugguuccggagagggagccugagagauggcuacuacguccaaggaug
gcagcaggcgcgaaacuugccuaauccuuuggggaggcgguuaugagaag
ugaugugugugcgagugcaaaggggucgcaugugauuggagggcaagucg
ggugccagcagccgcgguaauaccugcuccaauagugucuaugguggaug
cugcaguuaaaauguccguagucuguguaugucuuugugugugauguuug
ugguuguguguggauguagugaguguguggcagaggacgaggggcacugg
auaguugggcgagaggugaaaugcgaagacccugacuggacgagcggaag
cgaaggcugugcucuuggacuaauguugcgaugaaggacgaaggcuagag
gaucgaaaucgauuagauaccguuuuaguucuagcaguaaacgaugccga
cuggacgggacaguguguguuguccaugagaaaucuugaguaugcggguu
cuggggauaguaugcucgcaagagugaaacuugaagagauugacggaagg
acaccacaaggaguggagugugcggcuuaauuugacucaacgcggggcaa
cuuaccggcucugaaggaugccugugagugcauggcaugaggcaugcggc
gguggugcauggccguuuuaaauggauggcgugagcuuugucuuaaguug
cguaagaugugagacccuuugacgguguucuacggagcaaggaggggaug
gaagagaacagguccguuaugcccugagaugaggcgggcugcacgcgcac
uacgauagauggcgcuucugccugcugugagggaugaagcuguguaaggg
gcuucugaacguggaauuccuaguaauagcggcugacgaagcugcuuuga
augugucccuguccuuuguacacaccgcccgucgcuaucuaagaugacgc
acuggacgaagaucggaaggucugaguccugaguguuagauaagauauaa
gucguaacauggcugcuguuggagaaccagcagcaggaucaguau

..<<<<..[.((((.>>>>.<<<<<<<<<..<<<<<.<.......<<<.<
<<..<<<......<<<.....>>>.....>>>......<<.........<
<<<<<..<<..<<<<<.....<<.<<...<<<<<<......>>>>>.>..
>>.>>.<<<<<....>>>>>..>>>>>.>>>>>>>>..<<<....<<<..
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<<<<<<....
>>>>...>>>>.>>.<<.<<<..........>>>.>>.<<<<....>>>>
...>>>>>>.........<<<....<<....>>..>>>...>..>>>>>.
........<<<<<<.<.......>.>>>>>>....<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>.......
...<<<((.....<<<<...<<<....<<<<<<<....<<<<<<<.....
..>>>>>>>..>>>>>>>...........<<<.<<..<<.<<<<<<<<.<
.<<<<<<<<...<..........>......>>>>>>>>..>>.......<
<....>>.>>>>>>>>>..>>..>>>...>>>...>>>>....<<<<<<<
...<..<<.<<.<.....>.>>.>>..>>>>>>>>..........<<<.<
<.<<<<<<.<<<...>>>.>>>>>>..<<..))>>....>>.....>>>.
>>>.<<.......<<<<....>>>>.....>>..)))).]<<<<<.<<<<
<<<..<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<.<<<......<<<<<.....<<<.....>>>..>>>>>....<
<<.<<<..<<.<<<<<<....<<<...<<<....>>>..<<........>
>......>>>.....<<........<<<<<....>>>>>..........>
>.....>>>.>>>.....>>>>>>>>....>>>.>>>...>>.>>>>>>>
>.....<<..<<<......>>>..>>....<....<<<<<<........>
>>>>>....>.....>>>>>>....<.<<<<<<.......>>>>>>.>..
....>>...>>>>>>>>>>.>>....<..<<.<..<<<<<.<...<<<<<
.<.<<<<..<<<<<....>>>>>..>>>>.>.>>>>>...>.>>>>>...
>.>>...>.....<<<<<<<<<....>>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qep Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): R26 F29 R35 G36 G38 I39 R40 I41 Y84 N86 Q88 M111 R120 R122 L126 K131 R133 Q135 R136 T137 K138 S139 N140 R142
• Binding residue (residue number reindexed from 1): R25 F28 R34 G35 G37 I38 R39 I40 Y83 N85 Q87 M110 R119 R121 L125 K130 R132 Q134 R135 T136 K137 S138 N139 R141

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qep, PDBe:7qep, PDBj:7qep
• PDBsum: 7qep
• UniProt: Q8SRP2|RS18_ENCCU Small ribosomal subunit protein uS13 (Gene Name=RPS18)