Structure of PDB 7miz Chain C5 Binding Site BS01

Receptor Information

>7miz Chain C5 (length=426) Species: 5811 (Toxoplasma gondii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MREIVHVQGGQCGNQIGAKFWEVISDEHGIDPTGTYCGDSDLQLERINVF
YNEATGGRFVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNN
WAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTL
LISKVREEYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQ
VIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCLRFPGQLNSDL
RKLAVNLIPFPRLHFFLIGFAPLTSRGSQQYRALSVPELTQQMFDAKNMM
CASDPRHGRYLTASAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNMK
SSVCDIPPKGLKMSVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQ

Ligand information

>7miz Chain 23 (length=20) Species: 5811 (Toxoplasma gondii) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

LPFNAQSCYRSEYVAKPLPP

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7miz Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins.
Resolution	3.4 Å
Binding residue (original residue number in PDB)	S40 Q43 Q245 R320 D355 I356
Binding residue (residue number reindexed from 1)	S40 Q43 Q245 R320 D355 I356

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005200	structural constituent of cytoskeleton
GO:0005525	GTP binding

	Biological Process
GO:0000226	microtubule cytoskeleton organization
GO:0000278	mitotic cell cycle
GO:0007017	microtubule-based process

	Cellular Component
GO:0005737	cytoplasm
GO:0005874	microtubule

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Cellular Component

External links

PDB	RCSB:7miz, PDBe:7miz, PDBj:7miz
PDBsum	7miz
PubMed	34031406
UniProt	I7BFC9

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