Structure of PDB 9bju Chain C Binding Site BS01
Receptor Information
>9bju Chain C (length=142) Species:
9606
(Homo sapiens) [
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PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIH
SYRGHLWLFRDAGTHDGLLVNQTELFVPSLNQPIFANITLPVYTLKERCL
QVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQER
Ligand information
>9bju Chain Z (length=3) Species:
32630
(synthetic construct) [
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VPF
Receptor-Ligand Complex Structure
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PDB
9bju
Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability
Resolution
2.47 Å
Binding residue
(original residue number in PDB)
F76 P86 W88 Y98 P99 I109 H110 S111 Y112 H115 W117
Binding residue
(residue number reindexed from 1)
F16 P26 W28 Y38 P39 I49 H50 S51 Y52 H55 W57
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:9bju
,
PDBe:9bju
,
PDBj:9bju
PDBsum
9bju
PubMed
UniProt
P40337
|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)
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