Structure of PDB 8yj6 Chain C Binding Site BS01

Receptor Information
>8yj6 Chain C (length=278) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSN
ADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGAS
EKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAKLE
KLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEG
TPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDS
IAKKGKPGDSYYAMMKWNLDKISEGLAK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8yj6 Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8yj6 Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Resolution1.37 Å
Binding residue
(original residue number in PDB)		H52 H124 E190 D265
Binding residue
(residue number reindexed from 1)		H36 H108 E174 D249
Annotation score4
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8yj6, PDBe:8yj6, PDBj:8yj6
PDBsum8yj6
PubMed38747382
UniProtP0A4G4|MTSA_STRP1 Iron ABC transporter substrate-binding lipoprotein MtsA (Gene Name=mtsA)

[Back to BioLiP]