Structure of PDB 8wh6 Chain C Binding Site BS01

Receptor Information

>8wh6 Chain C (length=463) Species: 10244 (Monkeypox virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GNKLFNIAQRILDTNSVLLTERGDHIVWINNSWKFNSEEPLITKLILSIR
HQLPKEYSSELLCPRKRKTVEANIRDMLVDSVETDTYPDKLPFKNGVLDL
VDGMFYSGDDAKKYTCTVSTGFKFDDTKFVEDSPEMEELMNIINDIQPLT
DENKKNRELYEKTLSSCLCGATKGCLTFFFGETATGKSTTKRLLKSAIGD
LFVETGQTILTDVLDKGPNPFIANMHLKRSVFCSELPDFACSGSKKIRSD
NIKKLTEPCVIGRPCFSNKINNRNHATIIIDTNYKPVFDRIDNALMRRIA
VVRFRTHFSQPSGREAAENNDAYDKVKLLDEGLDGKIQNNRYRFAFLYLL
VKWYKKYHIPIMKLYPTPEEIPDFAFYLKIGTLLVSSSVKHIPLMTDLSK
KGYILYDNVVTLPLTTFQQKISKYFNSRLFGHDIESFINRHKKFANVSDE
YLQYIFIEDISSP

Ligand information

>8wh6 Chain T (length=3) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8wh6 Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Resolution	3.27 Å
Binding residue (original residue number in PDB)	P540 R585 F588
Binding residue (residue number reindexed from 1)	P218 R263 F266

External links

PDB	RCSB:8wh6, PDBe:8wh6, PDBj:8wh6
PDBsum	8wh6
PubMed	39167653
UniProt	Q5IXS3

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