Structure of PDB 8w5z Chain C Binding Site BS01

Receptor Information
>8w5z Chain C (length=333) Species: 6944 (Ixodes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFTYVSPDRYVLGPDSRRYPYNNDMPLIFIGGMPRSGTTLVRVLLDAHPD
VRCGEETRVIPRLLSLKQQWVKNPTEMHRLLEGGITDEVLDAAMSAFILE
VIVRHGKPAPRLCNKDPFTLRAAVYLHRLFPRAKFLLMIRDGRAVVHSII
TRKVTITGYDLSDYRQCLKRWNAAMTSMYAQCQQLGPGLCLPVYYEQLVL
HPRAWMQRILAFLEVPWNDSVLHHEQLINQSGIALSKLERSTDQVIKPIN
LGALSKWVGHIPEDVVRDMAKVAPMLAQLGYDPAANPPDYGQPDNFVLNN
TLEIKKKMEEWQARERELEEHRELIKQSIAKKK
Ligand information
Receptor-Ligand Complex Structure
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PDB8w5z Crystal structure of tick tyrosylprotein sulfotransferase reveals the activation mechanism of the tick anticoagulant protein madanin.
Resolution1.55 Å
Binding residue
(original residue number in PDB)
E115 R118
Binding residue
(residue number reindexed from 1)
E76 R79
Enzymatic activity
Enzyme Commision number 2.8.2.20: protein-tyrosine sulfotransferase.
Gene Ontology
Molecular Function
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation

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Molecular Function

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Biological Process
External links
PDB RCSB:8w5z, PDBe:8w5z, PDBj:8w5z
PDBsum8w5z
PubMed38354785
UniProtB7Q097

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