Structure of PDB 8vpg Chain C Binding Site BS01

Receptor Information
>8vpg Chain C (length=537) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDILY
DLFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDSL
TNKNLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEKKYKKFLLEKYSEVY
KDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESLSGKDLREYIKSNVN
VQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYIDVFKIKNEDICINKF
ETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKCKYSLED
IAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKS
EYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWG
REKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSY
EYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIE
NLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLGI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vpg Quinoline-based compounds can inhibit diverse enzymes that act on DNA
Resolution3.05 Å
Binding residue
(original residue number in PDB)		Y30 N165 Y168 H171 K173 K193 Y221 S227 F253 I256 G257 Q346 R432 W439 R441 K456 Y476 K511 M513 S514 Y521 P522 N523
Binding residue
(residue number reindexed from 1)		Y3 N125 Y128 H131 K133 K153 Y181 S187 F213 I216 G217 Q306 R392 W399 R401 K416 Y436 K471 M473 S474 Y481 P482 N483
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