Structure of PDB 8v6j Chain C Binding Site BS01

Receptor Information
>8v6j Chain C (length=435) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGDRKGDLYPSSLQFYQHPPTENISLIEFETFAIERLKLLKAVENLGVSY
VKNSEEYSKKLELELRKLKFPYRPLHEEISDDVYDLRRKDHISHFILRLA
YCQSEDLRRWFIQQEMDLFKFRFGLLTKESVQEFLKLNDLQYVAISEDEK
NMHKEDLMNSSFGLSLTKMEDTEFYKVPFQAALDLVRPRKVFLWRGFAFI
PHKDIVSIVLNDFRAKLSKALALSARSLPVVQSDERLQPLLNHLSHSYII
SLEQIDGFAAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTLE
QALQFWRLEFTKGKVDSEKFDKVYAYSIRHNYGKEGKRTDYTPYSCMKVI
LSNPPSQGDYHGCPFRHSDPELLKQKLQSFKVPSSGINQILELVKGMHYQ
LACQKYFELTHSVDDCGFSLNHPNQYFAESQKLLT
Ligand information
Receptor-Ligand Complex Structure
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PDB8v6j A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase
Resolution11.11 Å
Binding residue
(original residue number in PDB)		M313 K349 Y353 H357 K364 T366 Y368 T369 Y371 S372 K375
Binding residue
(residue number reindexed from 1)		M286 K322 Y326 H330 K337 T339 Y341 T342 Y344 S345 K348
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
Cellular Component
GO:0005658 alpha DNA polymerase:primase complex
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v6j, PDBe:8v6j, PDBj:8v6j
PDBsum8v6j
PubMed38491139
UniProtA0A1L8G3G3

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