Structure of PDB 8v6g Chain C Binding Site BS01

Receptor Information
>8v6g Chain C (length=435) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGDRKGDLYPSSLQFYQHPPTENISLIEFETFAIERLKLLKAVENLGVSY
VKNSEEYSKKLELELRKLKFPYRPLHEEISDDVYDLRRKDHISHFILRLA
YCQSEDLRRWFIQQEMDLFKFRFGLLTKESVQEFLKLNDLQYVAISEDEK
NMHKEDLMNSSFGLSLTKMEDTEFYKVPFQAALDLVRPRKVFLWRGFAFI
PHKDIVSIVLNDFRAKLSKALALSARSLPVVQSDERLQPLLNHLSHSYII
SLEQIDGFAAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTLE
QALQFWRLEFTKGKVDSEKFDKVYAYSIRHNYGKEGKRTDYTPYSCMKVI
LSNPPSQGDYHGCPFRHSDPELLKQKLQSFKVPSSGINQILELVKGMHYQ
LACQKYFELTHSVDDCGFSLNHPNQYFAESQKLLT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8v6g A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase
Resolution11.16 Å
Binding residue
(original residue number in PDB)
H309 M313 K349 Y353 H357 Y368 T369
Binding residue
(residue number reindexed from 1)
H282 M286 K322 Y326 H330 Y341 T342
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
Cellular Component
GO:0005658 alpha DNA polymerase:primase complex
GO:1990077 primosome complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8v6g, PDBe:8v6g, PDBj:8v6g
PDBsum8v6g
PubMed38491139
UniProtA0A1L8G3G3

[Back to BioLiP]