Structure of PDB 8v6g Chain C Binding Site BS01
Receptor Information
>8v6g Chain C (length=435) Species:
8355
(Xenopus laevis) [
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TGDRKGDLYPSSLQFYQHPPTENISLIEFETFAIERLKLLKAVENLGVSY
VKNSEEYSKKLELELRKLKFPYRPLHEEISDDVYDLRRKDHISHFILRLA
YCQSEDLRRWFIQQEMDLFKFRFGLLTKESVQEFLKLNDLQYVAISEDEK
NMHKEDLMNSSFGLSLTKMEDTEFYKVPFQAALDLVRPRKVFLWRGFAFI
PHKDIVSIVLNDFRAKLSKALALSARSLPVVQSDERLQPLLNHLSHSYII
SLEQIDGFAAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTLE
QALQFWRLEFTKGKVDSEKFDKVYAYSIRHNYGKEGKRTDYTPYSCMKVI
LSNPPSQGDYHGCPFRHSDPELLKQKLQSFKVPSSGINQILELVKGMHYQ
LACQKYFELTHSVDDCGFSLNHPNQYFAESQKLLT
Ligand information
>8v6g Chain E (length=16) [
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tcacgcagtatcctgt
Receptor-Ligand Complex Structure
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PDB
8v6g
A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase
Resolution
11.16 Å
Binding residue
(original residue number in PDB)
H309 M313 K349 Y353 H357 Y368 T369
Binding residue
(residue number reindexed from 1)
H282 M286 K322 Y326 H330 Y341 T342
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0046872
metal ion binding
GO:0051539
4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006269
DNA replication, synthesis of primer
GO:0006270
DNA replication initiation
Cellular Component
GO:0005658
alpha DNA polymerase:primase complex
GO:1990077
primosome complex
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8v6g
,
PDBe:8v6g
,
PDBj:8v6g
PDBsum
8v6g
PubMed
38491139
UniProt
A0A1L8G3G3
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