Structure of PDB 8uw6 Chain C Binding Site BS01

Receptor Information
>8uw6 Chain C (length=380) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQ
PVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDG
KLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARY
FAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGV
NAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRI
CAWCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIP
GYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQ
AHQPDEYLETRFIKPTRELITQVIHHFCWH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8uw6 Chain C Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8uw6 Acetylornithine deacetylase from Escherichia coli, di-zinc form.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H80 D112 E169
Binding residue
(residue number reindexed from 1)		H77 D109 E166
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.1.16: acetylornithine deacetylase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008777 acetylornithine deacetylase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050897 cobalt ion binding
Biological Process
GO:0006526 L-arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uw6, PDBe:8uw6, PDBj:8uw6
PDBsum8uw6
PubMed39055043
UniProtP23908|ARGE_ECOLI Acetylornithine deacetylase (Gene Name=argE)

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