Structure of PDB 8urw Chain C Binding Site BS01

Receptor Information
>8urw Chain C (length=1080) Species: 32046 (Synechococcus elongatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAFHLPDLVAIQRNSFRWFLEEGLIEELESFSPITDYTGKLELHFLGKQY
KLKRPKYDVDEAKRRDGTYSVQMYVPTRLINKETGEIKEQEVFIGDLPLM
TDRGTFIINGAERVIVNQIVRSPGVYYKSERDKNGRLTHNASLIPNRGAW
LKFETDKNGLVWVRIDKTRKLSAQVLLKALGLSDNEIYDKLRHPEYYQKT
IDKEGQFSEDEALMELYRKLRPGEPPTVSGGQQLLESRFFDPKRYDLGRV
GRYKLNKKLGLNVADTVRTLTSEDILAAIDYLINLELDLGGCEVDDIDHL
GNRRVRSVGELLQNQVRVGLNRLERIIRERMTVSDSDSLSPASLVNPKPL
VAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFAVR
DIHPSHYGRICPIETPEGPNAGLIGSLATHARVNDYGFIETPFWRVEEGR
VRKDLAPVYMTADQEDDLRVAPGDVATDDAGYILGTTIPVRYRQDFTTTT
PERVDYVALSPVQIISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPE
RPLVGTGLEPQAARDSGMVITSPVDGTISYVDATHIEVTADTGEKYGYAL
QKYQRSNQDTCLNQRPIVFEGDRVQRGQVIADGSATEKGELALGQNILVA
YMPWEGYNYEDAILISERLVYDDVYTSIHIEKFEIEARQTKLGPEEITRE
IPNVGEDALRQLDENGIIRVGAWVESGDILVGKVTPKGESDQPPEEKLLR
AIFGEKARDVRDNSLRVPNGEKGRVVDVRLFTREQGDELPPGANMVVRVY
VAQKRKIQVGDKMAGRHGNKGIISRILPCEDMPYLPDGTPLDIVLNPLGV
PSRMNVGQVFECMLGWAGQLLDARFKVTPFDEMYGAEASRLTVNAKLSEA
REQTGQPWVFSDDEPGKIQVYDGRTGEPFDRPVTVGRAYMLKLVHLVDDK
IHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAYGAAYILQELLT
VKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLCLDIAVYKA
STEDYEEDKEVDLMADVNQRRTPSRPTYES
Ligand information
>8urw Chain N (length=40) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggcgcatgctgctctaggagaggtacacggcgactgccc
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8urw Cryo-EM structure of a cyanobacterial RNAP elongation complex with NusG and CTP.
Resolution2.79 Å
Binding residue
(original residue number in PDB)		G157 W159 K176 R253 R403
Binding residue
(residue number reindexed from 1)		G148 W150 K167 R244 R394
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8urw, PDBe:8urw, PDBj:8urw
PDBsum8urw
PubMed38354263
UniProtQ31N17|RPOB_SYNE7 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

[Back to BioLiP]