Structure of PDB 8ti7 Chain C Binding Site BS01
Receptor Information
>8ti7 Chain C (length=130) Species:
6956
(Dermatophagoides pteronyssinus) [
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GSWQSYVDNQICQHVDCTLAAIANIQDGSIWAKFEKDDKKISPKELKTIA
DTIRQNPNGFLETGIHIGGEKYICIQADNQLVRGRRGSSALCIVATNTCL
LAAATVDGYPAGQLNNVIEKLGDYLRSNNY
Ligand information
>8ti7 Chain D (length=12) Species:
32630
(synthetic construct) [
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PPPPPPPPPPPP
Receptor-Ligand Complex Structure
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PDB
8ti7
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Resolution
2.397 Å
Binding residue
(original residue number in PDB)
G1 S2 W3 Y6 Q10 W31 Y124 Y130
Binding residue
(residue number reindexed from 1)
G1 S2 W3 Y6 Q10 W31 Y124 Y130
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003779
actin binding
GO:0003785
actin monomer binding
Biological Process
GO:0042989
sequestering of actin monomers
GO:0044087
regulation of cellular component biogenesis
GO:0051128
regulation of cellular component organization
Cellular Component
GO:0005856
cytoskeleton
GO:0005938
cell cortex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8ti7
,
PDBe:8ti7
,
PDBj:8ti7
PDBsum
8ti7
PubMed
38662449
UniProt
A0A2L0EBJ5
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