Structure of PDB 8syp Chain C Binding Site BS01

Receptor Information
>8syp Chain C (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
Q
Ligand information
>8syp Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcagggcctctcggctgctgatcttcagctggttgctgagagttgcagca
ttgctgagtcttagcaatggatacttcccgattcccctcacaaaaatagg
tcagtctgtctggctagttctgtacttgcagacacagggcatgtggg
Receptor-Ligand Complex Structure
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PDB8syp Structural basis of cooperative targeting of the CX3CR1 nucleosome by PU.1 and C/EBPa
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K15 R17 R20 R32 R77
Binding residue
(residue number reindexed from 1)		K4 R6 R9 R21 R66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8syp, PDBe:8syp, PDBj:8syp
PDBsum8syp
PubMed38267599
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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