Structure of PDB 8syi Chain C Binding Site BS01

Receptor Information
>8syi Chain C (length=1061) Species: 32046 (Synechococcus elongatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FHLPDLVAIQRNSFRWFLEEGLIEELESFSPITDYTGKLELHFLGKQYKL
KRPKYDVDEAKRRDGTYSVQMYVPTRLINKETGEIKEQEVFIGDLPLMTD
RGTFIINGAERVIVNQIVRSPGVYYKSERDKNGRLTHNASLIPNRGAWLK
FETDKNGLVWVRIDKTRKLSAQVLLKALGLSDNEIYDKLRHPEYYQKTID
KEGQFSEDEALMELYRKLRPGEPPTVSGGQQLLESRFFDPKRYDLGRVGR
YKLNKKLGLNVADTVRTLTSEDILAAIDYLINLELDLGGCEVDDIDHLGN
RRVRSVGELLQNQVRVGLNRLERIIRERMTVSDSDSLSPASLVNPKPLVA
AIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFAVRDI
HPSHYGRICPIETPEGPNAGLIGSLATHARVNDYGFIETPFWRVEEGRVR
KDLAPVYMTADQEDDLRVAPGDVATDDAGYILGTTIPVRYRQDFTTTTPE
RVDYVALSPVQIISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPERP
LVGTGLEPQAARDSGMVITSPVDGTISYVDATHIEVTADTGEKYGYALQK
YQRSNQDTCLNQRPIVFEGDRVQRGQVIADGSATEKGELALGQNILVAYM
PWEGYNYEDAILISERLVYDDVYTSIHIEKFEIEARQTKLGPEEITREIP
NVGEDALRQLDENGIIRVGAWVESGDILVGKVTPKGEARDVRDNSLRVPN
GEKGRVVDVRLFTREQGDELPPGANMVVRVYVAQKRKIQVGDKMAGRHGN
KGIISRILPCEDMPYLPDGTPLDIVLNPLGVPSRMNVGQVFECMLGWAGQ
LLDARFKVTPFDEMYGAEASRLTVNAKLSEAREQTGQPWVFSDDEPGKIQ
VYDGRTGEPFDRPVTVGRAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGG
KAQQGGQRFGEMEVWALEAYGAAYILQELLTVKSDDMQGRNEALNAIVKG
KAIPRPGTPESFKVLMRELQSLCLDIAVYKASTEDYEEDKEVDLMADVNQ
RRTPSRPTYES
Ligand information
Receptor-Ligand Complex Structure
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PDB8syi Cryo-EM structure of a cyanobacterial RNAP elongation complex
Resolution2.94 Å
Binding residue
(original residue number in PDB)
W159 D175 E402 R403
Binding residue
(residue number reindexed from 1)
W148 D164 E391 R392
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8syi, PDBe:8syi, PDBj:8syi
PDBsum8syi
PubMed38354263
UniProtQ31N17|RPOB_SYNE7 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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