Structure of PDB 8rcd Chain C Binding Site BS01

Receptor Information
>8rcd Chain C (length=310) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAK
ADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG
SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPER
LLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLI
VDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVV
AQVPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAI
NADGVGDAKD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rcd RAD51 protects abasic sites to prevent replication fork breakage.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
R241 Q242 V270 A271 V273 K285 G288 G289 N290
Binding residue
(residue number reindexed from 1)
R221 Q222 V250 A251 V253 K256 G259 G260 N261
External links
PDB RCSB:8rcd, PDBe:8rcd, PDBj:8rcd
PDBsum8rcd
PubMed39178838
UniProtQ06609|RAD51_HUMAN DNA repair protein RAD51 homolog 1 (Gene Name=RAD51)

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