Structure of PDB 8qu4 Chain C Binding Site BS01

Receptor Information
>8qu4 Chain C (length=81) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHT
EDNKRRTLQRNDIAMAITKFDQFDFLIDIVP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8qu4 Binding dynamics of a stapled peptide targeting the transcription factor NF-Y.
Resolution1.38 Å
Binding residue
(original residue number in PDB)
Q110 D112 F113 D116
Binding residue
(residue number reindexed from 1)
Q72 D74 F75 D78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8qu4, PDBe:8qu4, PDBj:8qu4
PDBsum8qu4
PubMed38470946
UniProtQ13952|NFYC_HUMAN Nuclear transcription factor Y subunit gamma (Gene Name=NFYC)

[Back to BioLiP]