Structure of PDB 8qfs Chain C Binding Site BS01

Receptor Information
>8qfs Chain C (length=393) Species: 866768 (Escherichia coli 'BL21-Gold(DE3)pLysS AG') [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQID
NAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDG
AILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVE
MEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIP
EPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKET
QKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKP
HTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMV
MPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS
Ligand information
>8qfs Chain B (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagucgguagagcagcguguccuugguucgauuccgag
uccgggcacca
<<<<<<<..<<<<........>>>>.<>.....<<<<<.......>>>>>
>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8qfs Structural basis for the toxicity of Legionella pneumophila effector SidH
Resolution2.7 Å
Binding residue
(original residue number in PDB)		P54 E55 N64 Y88 N91 S220 I221 V227 E260 R263 G276 L278 R284 R289 R319 H320 T321 G326 Y327 R328 Q330 T339 I364 E379 G380
Binding residue
(residue number reindexed from 1)		P53 E54 N63 Y87 N90 S219 I220 V226 E259 R262 G275 L277 R283 R288 R318 H319 T320 G325 Y326 R327 Q329 T338 I363 E378 G379
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0032045 guanyl-nucleotide exchange factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qfs, PDBe:8qfs, PDBj:8qfs
PDBsum8qfs
PubMed37923743
UniProtP0CE48|EFTU2_ECOLI Elongation factor Tu 2 (Gene Name=tufB)

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