Structure of PDB 8pk6 Chain C Binding Site BS01

Receptor Information
>8pk6 Chain C (length=235) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIFSESHKTVFVVDHCPYMAESCRQHSKSLWTCSVESSMEYCRIMYDIF
PFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECS
ILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSH
VRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDR
SKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFD
Ligand information
>8pk6 Chain D (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLERLQEILRKFLYLEREFRQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pk6 Basis of gene-specific transcription regulation by the Integrator complex.
Resolution3.21 Å
Binding residue
(original residue number in PDB)		L103 K147 M154 C158 E161 H166
Binding residue
(residue number reindexed from 1)		L102 K146 M153 C157 E160 H165
External links
PDB RCSB:8pk6, PDBe:8pk6, PDBj:8pk6
PDBsum8pk6
PubMed38906142
UniProtQ9NVM9|INT13_HUMAN Integrator complex subunit 13 (Gene Name=INTS13)

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