Structure of PDB 8pds Chain C Binding Site BS01

Receptor Information
>8pds Chain C (length=365) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGE
ILYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSL
GKIKNNKGEDLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQ
RPSAPDTPIILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPR
MDIPKIARSFYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQ
AYGAGQTMLRWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESG
LLHLRQSPKAGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSA
AESYAKSLKESNKIN
Ligand information
Receptor-Ligand Complex Structure
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PDB8pds Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K171 A173 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 S314 I334 M337 Y338 R339
Binding residue
(residue number reindexed from 1)		K171 A173 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 S314 I334 M337 Y338 R339
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8pds, PDBe:8pds, PDBj:8pds
PDBsum8pds
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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