Structure of PDB 8kcx Chain C Binding Site BS01

Receptor Information
>8kcx Chain C (length=571) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGADFDHVYSGVVNLSTENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPV
LVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSEATNETGPLQQ
LIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTASPSQPQYFLYKF
PKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKK
AAITLQKKDFPGEQFFVVFVIKPEDYACGGSFLQRKKNLEVTIVPSIKES
VYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFKIYFWNIITIAVFYALPVI
QLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFL
FLLIVLRRDILHRRALEAHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQ
FDTSFMYMIAGLCMLKLYQTYASFAVVIMVTVLGVVFVWFWVIFSAIHVL
ASLALSTQIYYMGDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPL
FCIVATAVMWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIW
HFLSATALFFSFLVLLTLDDD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8kcx Chain C Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8kcx Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		H563 H791 H795
Binding residue
(residue number reindexed from 1)		H391 H547 H551
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8kcx, PDBe:8kcx, PDBj:8kcx
PDBsum8kcx
PubMed38811802
UniProtQ9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 (Gene Name=SIDT1)

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