Structure of PDB 8in8 Chain C Binding Site BS01

Receptor Information
>8in8 Chain C (length=470) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLSQLAAHSTIPEPLLLFKDNRTDTHPLRGLSQYGPYSACFNLPGQVRLA
YLAPTEHMRKLDAIVRELQNPATPKEATNYYVEYGGFEKVFKVPLVMPQE
HLRCLALDECHGVAANGNGLALADKIVQSMSGLFRQKHAFDVLLVYLPAS
WKKCFEYDGFDLHDRIKAKVAPLNLPIQIINDTALTRQCRANVMWGVSVA
LYAKAGGIPWKLADWDKDEAYIGLSYAIKKNAEGQEYTTCCSQVFDPDGT
GFEFVAYDTREFITDRKGNPYLSYQEMQSVLSKSLHLYQSSHNGRMPRKI
FIHKTTHFTEDEIQGAFDSFSSSTEIELVQIIQSTNWYGLKVDGKKGDKP
VAPASYPVDRGLYQPLTESECLLWTQGSVMGVNQQNPGQPVFKEAALTPL
PNPIMLRRFSGNGGWHATCSSILALTKVDWNNNTLYKKLPVTLVYSQVFA
DVVKQTPEIVNEIYDYRFFM
Ligand information
>8in8 Chain I (length=24) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaugguuucuuagacgucguuu
........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8in8 Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		F158 D164 H166 I182 N184 R190 E239 N272 Q379 K396 L400 T401 N434 N435 N436 K440
Binding residue
(residue number reindexed from 1)		F155 D161 H163 I179 N181 R187 E236 N269 Q376 K393 L397 T398 N431 N432 N433 K437
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
Biological Process
GO:0008150 biological_process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8in8, PDBe:8in8, PDBj:8in8
PDBsum8in8
PubMed37311833
UniProtQ74DF5

[Back to BioLiP]