Structure of PDB 8i24 Chain C Binding Site BS01

Receptor Information
>8i24 Chain C (length=1164) Species: 637887 (Acetivibrio thermocellus DSM 1313) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VHPVKLGRNVRMSYSKIDEVIDMPNLIEIQKNSYEQFLKEGFKEVFKDVN
PITDYTGNLILEFVDYSLDEPPKYSVDECKERDATYAAPLKVKVRLINKE
TGEVKEQEIFMGDFPLMTETGTFIINGAERVIVSQLVRSPGIYYAMKIDK
AGKQLFSNTVIPNRGAWLEYETDSNDVLSVRIDRTRKLPLTVLVRALGYG
TDLEITELFGEDERILATIQKDSTKTEEEGLLEIYKRLRPGEPPTVESAK
ALLHGLFFDPKRYDLAKPGRFKFNKKLSIAARIHGFIAGENIKDPDTGEI
IVAEGETISREKAETIQNAGVNTVILRVDGKNVKVIGNDMVDIKRYVDFD
PKEIGINEKVKRDVLMEILEEYKGKGDDAIKKALQERIDDLIPKHITKED
IISSISYIIGLSYGIGSTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERV
VRERMTIQDLDVVTPQALINIRPVAAAIKEFFGSSQLSQFMDQTNPLAEL
THKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLIGS
LSTYARVNEYGFIETPYRKVSKEEPGKVTNEIVYLTADEEDEYIIAQANE
PLDEEGRFISNKVVCRYKEEFIEVDPSKIDFMDVSPKQIVSVATSMIPFL
ENDDANRALMGANMQRQAVPLIKTESPIVGTGIEYRAARDSGVVILAKNP
GVVEKVTANEIIIRTKDGKRDTYKLLKYMRSNQGTCINQRPIVKKGEEVE
AGDVIADGPSTDNGEIALGKNVLVGFMTWEGYNYEDAILISERLVKDDVF
TSIHIEEYEAEARDTKLGPEDITREIPNVSEDALKDLNSEGIIRIGAEVR
AGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIV
VDVKIFTRENGDELAPGVNKLVRVYVAQKRKISVGDKMAGRHGNKGVISR
ILPVEDMPFLPDGTPLDIVLNPLGVPSRMNIGQVLEVHLGYAAKALGWKV
ATPVFDGATEEDIVQTLRKAGLAEDGKSILYDGRTGEPFENRVTVGYMYM
LKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYG
AAYTLQEILTVKSDDVVGRVKTYEAIVKGENVPEPGIPESFKVLIKELQS
LCLDVKVYSEEQEE
Ligand information
>8i24 Chain O (length=58) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caatgcgacataaaaccattccggtatacgaatcgatataagaataaggg
gtgaaatt
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i24 Structure of the transcription open complex of distinct sigmaI factors
Resolution3.36 Å
Binding residue
(original residue number in PDB)		W168 R519
Binding residue
(residue number reindexed from 1)		W167 R518
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i24, PDBe:8i24, PDBj:8i24
PDBsum8i24
PubMed37833284
UniProtA3DIZ4|RPOB_ACET2 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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