Structure of PDB 8h8e Chain C Binding Site BS01

Receptor Information
>8h8e Chain C (length=285) Species: 8364 (Xenopus tropicalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TCLKNFFSVLLILVYLLLMGVAVFLVYQTITDFRDKLKHPVMSVSYKEVN
MYDAPGIALYPGKARLLSCEHHWYDHIPPLKDPGQPGENTCVTQDISYID
PYTNKTMKHALIVQGPRDVRRRELVFLQFHLNETKQDFSAIDYLLFSSYE
AFLKSHDQVKFMQDCESSFSSWKFSGGFRTWVKMSLVKTKEEDGSQSVEF
RQETSVVNFIDRRETPDKGDQLFFVVFEWKDPYIQEIQDIITANPWSMIA
LLCSVFLVLFKAADFAKLSVKWMIKVRRRHLKKRA
Ligand information
>8h8e Chain G (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucuucgguaguauaguggucaguauccccgccugucacgcgggagaccgg
gguucgauuccccgccggagagcca
<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB8h8e Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state)
Resolution3.81 Å
Binding residue
(original residue number in PDB)		K335 R339
Binding residue
(residue number reindexed from 1)		K275 R279
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0061797 pH-gated chloride channel activity
Biological Process
GO:0006821 chloride transport
GO:0034220 monoatomic ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0034707 chloride channel complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8h8e, PDBe:8h8e, PDBj:8h8e
PDBsum8h8e
PubMed38942816
UniProtQ0V9Z3|PACC1_XENTR Proton-activated chloride channel (Gene Name=pacc1)

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