Structure of PDB 8gt7 Chain C Binding Site BS01

Receptor Information
>8gt7 Chain C (length=241) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMNYEEVIKKYKGNENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGS
VESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICT
DDDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISV
AVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYY
IIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Ligand information
>8gt7 Chain F (length=9) Species: 36329 (Plasmodium falciparum 3D7) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VNPLTKKGE
Receptor-Ligand Complex Structure
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PDB8gt7 Structure of falcipain and human Stefin A complex
Resolution3.28 Å
Binding residue
(original residue number in PDB)		Y11 K12
Binding residue
(residue number reindexed from 1)		Y11 K12
Enzymatic activity
Enzyme Commision number 3.4.22.-
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8gt7, PDBe:8gt7, PDBj:8gt7
PDBsum8gt7
PubMed
UniProtQ8I6U4|FPC2A_PLAF7 Falcipain-2a (Gene Name=FP2A)

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