Structure of PDB 8gaj Chain C Binding Site BS01

Receptor Information
>8gaj Chain C (length=127) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTGDTDQPIHIESDQQSLDMQGNVVTFTGNVIVTQGTIKINADKVVVTRP
GGEQGKEVIDGYGKPATFYQMQDNGKPVEGHASQMHYELAKDFVVLTGNA
YLQQVDSNIKGDKITYLVKEQKMQAFS
Ligand information
>8gaj Chain D (length=19) Species: 29025 (Podisus maculiventris) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KKPVPIIYCNRRTGKCQRM
Receptor-Ligand Complex Structure
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PDB8gaj Discovery, characterization, and redesign of potent antimicrobial thanatin orthologs from Chinavia ubica and Murgantia histrionica targeting E. coli LptA.
Resolution2.43 Å
Binding residue
(original residue number in PDB)		Q34 P35 I36 H37 I38 E39 S40 D41 Q43 V52 F54 N57 R76 Q81 G82 E84
Binding residue
(residue number reindexed from 1)		Q7 P8 I9 H10 I11 E12 S13 D14 Q16 V25 F27 N30 R49 Q54 G55 E57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001530 lipopolysaccharide binding
Biological Process
GO:0015920 lipopolysaccharide transport
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gaj, PDBe:8gaj, PDBj:8gaj
PDBsum8gaj
PubMed37416832
UniProtP0ADV1|LPTA_ECOLI Lipopolysaccharide export system protein LptA (Gene Name=lptA)

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