Structure of PDB 8ei5 Chain C Binding Site BS01

Receptor Information
>8ei5 Chain C (length=373) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRR
RLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQIN
PASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLK
DLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGE
SIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDE
KELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRI
RLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRL
DLPPYKSYEQLREKLLYAIEETE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ei5 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
Resolution2.6 Å
Binding residue
(original residue number in PDB)		F651 S654 W657 L668 Q674
Binding residue
(residue number reindexed from 1)		F159 S162 W165 L176 Q182
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity

View graph for
Molecular Function
External links
PDB RCSB:8ei5, PDBe:8ei5, PDBj:8ei5
PDBsum8ei5
PubMed37914719
UniProtO00308|WWP2_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP2 (Gene Name=WWP2)

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