Structure of PDB 8e2l Chain C Binding Site BS01

Receptor Information
>8e2l Chain C (length=461) Species: 8187 (Lates calcarifer) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEDEAQLIKTMFQITKVSNATLKKFGVRLFKPTKSLVFPWFAGPDSSLKG
LKLLSAQNTDTEKVTYNEATVPKISSYYNLFGLTLVGRMDSEVVLTGHEL
DTLAVSQATGLPSVALPRGVSCLPPMLLPYLEQFKRVTLWLGHDIRSWEA
SKIFSRKLGLRRCSLVRPGEDRPCPLEALARGKNLSRIIKTSIPAAHKSI
VSFKQLREDVYGELLNTEQVAGVKWTRFPELNRILKGHRKGELTVFTGPT
GSGKTTFISEVALDLCIQGVNTLWGSFQINNVRLAKIMLTQFAMQRLEEN
LEQYDFWADKFEELPLYFMTFHGQQNIKTVLDTMQHAVYLYDINHVIIDN
LQFMMGQIDKYAVQDHIIGAFRKFATNTSCHVTLIIHPRKEEDDRELQTA
SIFGSAKASQEADNVLILQEKKLVTCPGRRSLQVTKNRFDGDVGIFPLDF
IKSSLTFSAPI
Ligand information
Receptor-Ligand Complex Structure
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PDB8e2l Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase.
Resolution3.51 Å
Binding residue
(original residue number in PDB)
Y412 K441 G455
Binding residue
(residue number reindexed from 1)
Y361 K390 G404
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function

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Biological Process
External links
PDB RCSB:8e2l, PDBe:8e2l, PDBj:8e2l
PDBsum8e2l
PubMed36400570
UniProtA0A4W6C5C5

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