Structure of PDB 8dy7 Chain C Binding Site BS01

Receptor Information
>8dy7 Chain C (length=1118) Species: 54571 (Streptomyces venezuelae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASTAPLRISFAKIKEPLEVPNLLALQTESFDWLLGNAAWKARVEAALESG
QDVPTKSGLEEIFEEISPIEDFSGSMSLTFRDHRFEPPKNSIDECKDRDF
TYGAPLFVTAEFTNNETGEIKSQTVFMGDFPLMTNKGTFVINGTERVVVS
QLVRSPGVYFDSSIDKTSDKDIFSAKIIPSRGAWLEMEIDKRDLVGVRID
RKRKQSVTVLLKALGWTTEQILQEFGEYESMRATLEKDHTQGQDDALLDI
YRKLRPGEPPTREAAQTLLENLYFNPKRYDLAKVGRYKVNKKLGADEPLD
AGVLTTDDVIATIKYLVKLHAGETETIGENGNEIVVETDDIDHFGNRRLR
NVGELIQNQVRTGLARMERVVRERMTTQDVEAITPQTLINIRPVVASIKE
FFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGFEVRDVHPSH
YGRMCPIETPEGPNIGLIGSLASYGRVNAFGFIETPYRKVVDGQVTDEVD
YVTADEEDRFVIAQANAALDEELRFSENRVLVRKRGGEVDYVEPSDVDYM
DVSPRQMVSVATAMIPFLEHDDANRALMGANMMRQAVPLIKSEAPLVGTG
MEYRCATDAGDVLKAEKDGVVQELSADYITVANDDGTYITYRLHKFSRSN
QGTSVNQKVVVDEGDRVIEGQVLADGPATEDGEMALGKNLLVAFMPWEGH
NYEDAIILSQRLVQDDVLSSIHIEEHEVDARDTKLGPEEITRDIPNVSEE
VLADLDERGIIRIGAEVVAGDILVGKVTPKGETELTPEERLLRAIFGEKA
REVRDTSLKVPHGEIGKIIGVRVFDREEGDELPPGVNQLVRVYVAQKRKI
TDGDKLAGRHGNKGVISKILPIEDMPFLEDGTPVDIILNPLGVPSRMNPG
QVLEIHLGWLASRGWDVSGLADEWAQRLQAIGADKVAPGTNVATPVFDGA
REDELAGLLNHTIPNRDGERMVLPTGKARLFDGRSGEPFPDPISVGYMYI
LKLHHLVDDKLHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYG
AAYALQELLTIKSDDVTGRVKVYEAIVKGENIPEPGIPESFKVLIKEMQS
LCLNVEVLSSDGMSIEMR
Ligand information
>8dy7 Chain P (length=71) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aggccgctgctgctcaagaggggttcgcgggacggcatcggccaattggc
ccggtgtgtcgcacgatctgg
Receptor-Ligand Complex Structure
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PDB8dy7 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Resolution3.18 Å
Binding residue
(original residue number in PDB)		R224 R235 R470
Binding residue
(residue number reindexed from 1)		R192 R203 R438
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dy7, PDBe:8dy7, PDBj:8dy7
PDBsum8dy7
PubMed36888660
UniProtF2RIS5

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