Structure of PDB 8ddw Chain C Binding Site BS01

Receptor Information
>8ddw Chain C (length=695) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISKHTQLSPTDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLLHLMTKEWQ
LELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTG
VIRHVGDALKDHASKSRGKICTIGIAPWGIVENQEDLIGRDVVRPYQTMS
NPMSKLTVLNSMHSHFILADNGTTGKYGAEVKLRRQLEKHISLQKINTRI
GQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGH
KYSEVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDL
AILTALLKGANASAPDQLSLALAWNRVDIARSQIFIYGQQWPVGSLEQAM
LDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVR
DVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLNHFP
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASEN
DMVDDISQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNA
TCLQLAVAAKHRDFIAHTCSQMLLTDMNKYLGPYVMMIGKMMIDLLIAVF
NNTFFEVKSISNQVWKFQRYQLIMTFHERDYGLKLFITDDELKKVHDFEE
QCIEEYFREKDDRFNSSNDERIRVTSERVENMSMRLEEVNEREHS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ddw Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		I129 H132 T133 Q134 L135 S136 P137 T138 R159 E176
Binding residue
(residue number reindexed from 1)		I1 H4 T5 Q6 L7 S8 P9 T10 R31 E48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0051262 protein tetramerization
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ddw, PDBe:8ddw, PDBj:8ddw
PDBsum8ddw
PubMed36283409
UniProtQ5F4S7

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