Structure of PDB 8d3m Chain C Binding Site BS01

Receptor Information
>8d3m Chain C (length=343) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKLLNTLYVTQPDTYLSLDGDNVVLLKEQEKLGRLPLHNLEAIVGFGYT
GASPALMGYCAERNISITFLTKNGRFLARVVGESRGNVVLRKTQYRISEN
DQESTKIARNFITGKVYNSKWMLERMTREHPLRVNVEQFKATSQLLSVMM
QEIRNCDSLESLRGWEGQAAINYNKVFDQMILQQKEEFAFHGRSRRPPKD
NVNAMLSFAYTLLANDVAAALETVGLDAYVGFMHQDRPGRASLALDLMEE
LRGLYADRFVLSLINRKEMTADGFYKKENGAVLMTDEARKTFLKAWQTKK
QEKITHPYLGEKMSWGLVPYVQALLLARFLRGDLDEYPPFLWK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d3m PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution3.41 Å
Binding residue
(original residue number in PDB)		Y49 N73 N215 R289 K290 L293 Q297
Binding residue
(residue number reindexed from 1)		Y49 N73 N215 R289 K290 L293 Q297
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d3m, PDBe:8d3m, PDBj:8d3m
PDBsum8d3m
PubMed36272411
UniProtQ9KFX9

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