Structure of PDB 8cd8 Chain C Binding Site BS01

Receptor Information
>8cd8 Chain C (length=262) Species: 188937 (Methanosarcina acetivorans C2A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RMEIVKIPVVVHVVWNEEEENISDAQIQSQIDILNKDFRKLNSDVSQVPS
VWSNLIADLGIEFFLATKDPNGNQTTGITRTQTSVTFFTTSDEVKFASSG
GEDAWPADRYLNIWVCHVLKSEIGQDILGYAQFPGGPAETDGVVIVDAAF
GTTGTALPPFDKGRTATHEIGHWLNLYHIWGDELRFEDPCSRSDEVDDTP
NQADPNFGAPSYPHVSCSNGPNGDMFMNYMDYVDDKCMVMFTQGQATRVN
ACLDGPRSSFLA
Ligand information
Receptor-Ligand Complex Structure
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PDB8cd8 Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		Y190 A191 F193 H228 E229 H232 H238 Y292
Binding residue
(residue number reindexed from 1)		Y130 A131 F133 H168 E169 H172 H178 Y232
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8cd8, PDBe:8cd8, PDBj:8cd8
PDBsum8cd8
PubMed36857690
UniProtQ8TL28|ULIL_METAC Ulilysin (Gene Name=MA_3214)

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