Structure of PDB 8bpb Chain C Binding Site BS01

Receptor Information
>8bpb Chain C (length=126) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGGLMEQIQALLAPPKTDTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQ
CDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVF
DRFQDTVSQHVVKVDFLNRIHKKHPP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8bpb Chain C Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8bpb Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C289 C292 C315 H318
Binding residue
(residue number reindexed from 1)		C51 C54 C77 H80
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8bpb, PDBe:8bpb, PDBj:8bpb
PDBsum8bpb
PubMed37137925
UniProtQ96QT6|PHF12_HUMAN PHD finger protein 12 (Gene Name=PHF12)

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