Structure of PDB 8b1t Chain C Binding Site BS01

Receptor Information
>8b1t Chain C (length=1080) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQWLQMTL
SQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLP
QLLEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWE
TGHLVEGLGEAQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESA
TTCPPGLPSRVFICGISALPPVYLQALQALGKHIEIHLLFTNPCRYYWGD
IKDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNLLHNIQSD
ILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHD
RLLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISD
RRARQSHPVLEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLR
YLRQWVNESGIRWGIDDDNVRELELPATGQHTWRFGLTRMLLGYAMESAQ
GEWQSVLPYDESSGLIAELVGHLASLLMQLNIWRRGLAQERPLEEWLPVC
RDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGLGAQYGDAVPLSLLRDEL
AQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMNDGVYPRQLAP
LGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNSE
RFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDP
QNYQPGERQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFW
AHPVRAFFQMRLQVNFRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQ
DDAERLFRRFRAAGDLPYGAFGEIFWETQCQEMQQLADRVIACRQPGQSM
EIDLACNGVQITGWLPQVQPDGLLRWRPSLLSVAQGMQLWLEHLVYCASG
GNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREGMSAPLLVLPES
GGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDIWYQ
RLWRQLTPETMEAIVEQSQRFLLPLFRFNQ
Ligand information
>8b1t Chain X (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tttttttttttttctaatgcgagcactgctagcagtgctcgcattagatt
t
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8b1t Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R839 R846 Q850 L875 Y878 R968 S970 L971 N1078 M1079 M1080 V1081
Binding residue
(residue number reindexed from 1)		R798 R805 Q809 L834 Y837 R927 S929 L930 N1037 M1038 M1039 V1040
Enzymatic activity
Enzyme Commision number 3.1.11.5: exodeoxyribonuclease V.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008854 exodeoxyribonuclease V activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0009314 response to radiation
GO:0032508 DNA duplex unwinding
GO:0044355 clearance of foreign intracellular DNA
Cellular Component
GO:0009338 exodeoxyribonuclease V complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b1t, PDBe:8b1t, PDBj:8b1t
PDBsum8b1t
PubMed36533901
UniProtP07648|RECC_ECOLI RecBCD enzyme subunit RecC (Gene Name=recC)

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