Structure of PDB 8ati Chain C Binding Site BS01

Receptor Information
>8ati Chain C (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMY
HTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVE
ETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGET
LGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDL
LYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALA
QALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLE
MREAAATEIRRAITGRIPESLRNCVNKEFF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ati Human CtBP2(31-364) in complex with RAI2 peptide(315-322)
Resolution2.6 Å
Binding residue
(original residue number in PDB)		M48 V57 A58 F59 C60 H69
Binding residue
(residue number reindexed from 1)		M16 V25 A26 F27 C28 H37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:8ati, PDBe:8ati, PDBj:8ati
PDBsum8ati
PubMed
UniProtP56545|CTBP2_HUMAN C-terminal-binding protein 2 (Gene Name=CTBP2)

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