Structure of PDB 8a6z Chain C Binding Site BS01

Receptor Information

>8a6z Chain C (length=340) Species: 80249 (Phaedon cochleariae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GSFSKEESREFMAIFPDIVRDLTDHTDIPEVTKRFAKVLQYNVPTGKKTR
GLSTVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRSE
TRRGQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIELF
HDVNFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLPV
SLGMYLADMYDPEQHRQAKTILMEIGEFFQIQDDFLDAFGDSQVTGKVGT
DIKEGKCSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIELGL
PATFAVYEEESFNIIRTHIHQGLPHDLFFKIMKKIYKRDA

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

8a6z Chain C Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8a6z Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	D179 D183
Binding residue (residue number reindexed from 1)	D93 D97
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.5.1.1: dimethylallyltranstransferase.

Gene Ontology

	Molecular Function
GO:0004659	prenyltransferase activity
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

	Biological Process
GO:0008299	isoprenoid biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:8a6z, PDBe:8a6z, PDBj:8a6z
PDBsum	8a6z
PubMed	37308711
UniProt	M1JS91

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