Structure of PDB 7zmb Chain C Binding Site BS01

Receptor Information
>7zmb Chain C (length=441) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQDGFQGTRLIPTGADFQSPPDPFIDEGARDNAANYGVQKSRSGVDEDSV
EGRKVRHYTVNFGPQHPAAHGVLRLILELNGEEIVRADPHVGLLHRGTEK
LCEYKTYMQALPYFDRLDYVSMMTNEQVFSLAVEKLLNIEIPPRAKFIRT
MFGEITRILNHLMSVLSHAMDVGALTPFLWGFEEREKLMEFYERVSGARL
HAAYVRPGGVHQDIPVGLLDDIYQWATQFGDRIDETEEMLTDNRIWINRL
KGVGVVSAADALNLSFTGVMLRGSGVPWDVRKSSPYDAYDQVEFDVPVGI
NGDCYDRYLCRMEEFRQSLRIIHQCLNKMPAGPVRYEDYKITPPPRAAMK
ENMEALIHHFLLFTKGYAVPPGDTYTAIEAPKGEMGVYVVSDGSERPYRV
HIRAPGFAHLSGFDHITRGHLLADAVAVIGTMDLVFGEVDR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7zmb Chain K Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zmb Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R174 H259
Binding residue
(residue number reindexed from 1)		R116 H201
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0051287 NAD binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zmb, PDBe:7zmb, PDBj:7zmb
PDBsum7zmb
PubMed36427319
UniProtG0SCG0

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