Structure of PDB 7z71 Chain C Binding Site BS01

Receptor Information
>7z71 Chain C (length=189) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIPSNTDYPGPHSFDVSFQATWTYSTELKKLYCQIAKTCPIQIKVMTPPP
QGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGN
SHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP
ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7z71 Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7z71 Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C205 H208 C269 C273
Binding residue
(residue number reindexed from 1)		C74 H77 C138 C142
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z71, PDBe:7z71, PDBj:7z71
PDBsum7z71
PubMed35717504
UniProtQ9H3D4|P63_HUMAN Tumor protein 63 (Gene Name=TP63)

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