Structure of PDB 7yzp Chain C Binding Site BS01

Receptor Information
>7yzp Chain C (length=448) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAI
CLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNR
ARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRS
MLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTEL
EKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLTHQKLRENTTSQGEI
RQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFA
QGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTR
TLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALD
ALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAV
Ligand information
>7yzp Chain F (length=59) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaagccagacattaacgcttctggatagcgtccagaagcgttaatgtc
tggcttctg
Receptor-Ligand Complex Structure
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PDB7yzp Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		S65 S67 K130 K167 K194 S889 K890 K894
Binding residue
(residue number reindexed from 1)		S65 S67 K130 K167 K194 S290 K291 K295
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008296 3'-5'-DNA exonuclease activity
GO:0016887 ATP hydrolysis activity
GO:1990238 double-stranded DNA endonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
Cellular Component
GO:1990391 DNA repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yzp, PDBe:7yzp, PDBj:7yzp
PDBsum7yzp
PubMed35987200
UniProtP13458|SBCC_ECOLI Nuclease SbcCD subunit C (Gene Name=sbcC)

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